GitHub Advisoryadvisory · PyPI
GHSA-vjg6-gm8m-v5g6 Open Babel has out-of-bounds write in MOL2 attribute/value parser
HIGH
Official page ↗
- Aliases
- CVE-2022-43607
- Ecosystem
- PyPI
- Packages
- openbabel
- Severity
- High
- CVSS vector
- CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H
- Weaknesses
- CWE-119, CWE-787
- Reviewed
- 2026-07-01
Affected packages
• PyPI openbabel: < 3.2.0 → fixed in 3.2.0
Description
Summary
A memory-safety vulnerability in Open Babel's MOL2 parser allowed an
out-of-bounds write when reading a crafted input file.
Details
The flaw was in the attribute/value parsing path of the MOL2 reader.
An over-long attribute or value caused the parser to write past the
end of a fixed-size destination buffer.
Impact
Open Babel is a C++ library and CLI used to read and write chemistry
file formats; it is shipped by Linux distributions and embedded in
services that may parse untrusted input. Triggering this vulnerability
requires the victim to open a malicious MOL2 file with the `obabel`
tool, the `OBConversion` API, or any of the language bindings (Python,
Ruby, Java, R, Perl, C#, PHP).
Affected versions
All releases up to and including 3.1.1.
Patched version
3.2.0 (released 2026-05-26).
Patch
Fix commit: https://github.com/openbabel/openbabel/commit/4110d59a
A minimized reproducer for this CVE is checked in under
`test/files/fuzz_regress/` and is exercised on every CI build under
ASAN+UBSAN by the `fuzzregresstest` harness.
Credit
Reported by Cisco TALOS.
Related
Alias · CVE (1)
- CVE-2022-43607 An out-of-bounds write vulnerability exists in the MOL2 format attribute and value functionality of Open Babel 3.1.1 and master commit… vulnerability
References
- https://github.com/openbabel/openbabel/security/advisories/GHSA-vjg6-gm8m-v5g6 web
- https://nvd.nist.gov/vuln/detail/CVE-2022-43607 advisory
- https://github.com/openbabel/openbabel/commit/4110d59ada242139fb02098e1e1faff57ac4dd51 web
- https://github.com/openbabel/openbabel package
- https://talosintelligence.com/vulnerability_reports/TALOS-2022-1664 web
- https://www.talosintelligence.com/vulnerability_reports/TALOS-2022-1664 web